Supporting cell survival after cochlear implant surgery.
Laryngoscope. 2019 01;129(1):E36-E40
Authors: deTorres A, Olszewski RT, Lopez IA, Ishiyama A, Linthicum FH, Hoa M
Supporting cells (SCs) provide structure and maintain an environment that allows hair cells to receive and transmit signals in the auditory pathway. After insult to hair cells and ganglion cells, SCs respond by marking unsalvageable cells for death and maintain structural integrity. Although the histopathology after cochlear implantation has been described regarding hair cells and neural structures, surviving SCs in the implanted ear have not. We present a patient whose posthumous examination of an implanted cochlea demonstrated SC survival. This finding has implications for SC function in maintaining electrical hearing and candidacy for future hair cell regeneration therapies. Laryngoscope, 129:E36-E40, 2019.
PMID: 30325510 [PubMed – indexed for MEDLINE]